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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'add3b3d5c2ca7f1d8ba35279d870d035ecd8fa440729b50aaef7dd8924248d39' 
  AND token = 'oEKG7Wz4/8RmPqyycWeFLJYu9eqaxObNyNZYwSi/o0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}