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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8756975045e6450d1fc95e0d2bca439818d736f724f2086732a5e539587606' 
  AND token = 'EhytG5dsda4Coun06lT2ZNfXjnZcW1UasFSu6M2CdIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}