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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f579e3e2d75a455ad8da2f3fc33f508777e828728d0259969dceffadaa5a8fd' 
  AND token = 'nRCznTIsrlXj4nqoNTdLrZqzV3QxYpkXFydaPC0CvHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}