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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0107e4e8931d1267c056fdd77d87d3ec4603ab3ca8b92ba793907491e58323' 
  AND token = 'Trdh6R/iphndo3JrWeiixtXnIN6UwBTJy2z4IEP1n2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}