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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a02dcdb3121af62723e3982ba847c3c0e5bc3dc0143c3fff32cdac2edb8ee0' 
  AND token = 'QL8IXfcuK8sAvlNpI9WoTeiqoo6IDrbjWwqD3HM94uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}