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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1032f3adb60b038f41398b0f02394730793cd0f1f376ac4c35daeea16ae338f4' 
  AND token = 'PXT8vUVlR6AwlnF3ZKTWwIXz0a47tORT+I3XgYc+jWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}