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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02ce095b4857cdd7dce33887b644f748e18290e94f4ea48fcebbb59a0969d4c0' 
  AND token = 'KX2b5TbCUaMHIt2OrqlOv2wqnZMstT32uT2kSivQNPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}