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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f77adba6d5152bf7a9dbf496d662bfa189a532a60fbb2f59590ce49013bbd2' 
  AND token = 'kVor6DPiNYWon2qmKZ46+LFAyzAnqbhHWXGhkT53oo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}