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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e63e60261fe01d39d87fcda92b8de0a39832dda84a558ead6585bcca3ade105' 
  AND token = '3ZsA/MCh23yTmhoHFN+zoNblxuRS0QziA4vtd86DZKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}