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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0d7282e8debe6e50d0f07b4b745d817f97d481e6cf7151a78a595304550df8' 
  AND token = 'J8FyCzhk1O2QiUmdrHJ0v44z57poD9fAI00mSR6fik8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}