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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8664149b76612aa03de9c8f4b09bdb6ab43436febcc52332c71df26920b1402f' 
  AND token = '/1KE+nt1BJ6D0FwnsTunZDCl6H0BPKxqOCBxDAq3WUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}