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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659294f5058db5235436b8a7dd01c352e6ab31d33dbc5ac65ea5e89c006e4f9c' 
  AND token = 'FE8rRuraR4/YFgLoCZxXI/LgvPAB9FPdW+xwaCEWdJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}