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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ebb5057b74a51d410b19c69dddfdec27c5d0bf607537c3b5cdf816bafd7f681' 
  AND token = 'ivOWGG1/q9puVsC5N8X3X98Q1wiYPuGCZ2Cm3WSurOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}