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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753582451176536940327a7dbd55add80078c31cd8be714587c042a0ee0f9669' 
  AND token = 'xbhtett8IW3G8hR8v2uUk7nFPJ0qe0nS+MhPW1FiSgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}