SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af571d2d15ec77d3528ecd6d87e9721455ce0db9fce22e5a9fa1357db8d5b46d' 
  AND token = 'GYRVDgOQvlDFlRDvNVoo/fI9u1KaeAw8VQfoahi7Q9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}