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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e9c5e7df2133915e1ed6127198cf18a0c2ccbcb63b553f2a514c6698594057' 
  AND token = 'SH2QVEOqjKPpJRnQLiZntrT27O0+w72ZpltfdSTX308=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}