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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04607bb30eadb6cfb8f3b82cdd1c3b81d161d7ece4bc00227c08348864e4f8dc' 
  AND token = 'd1YlW4nq8Fr6+HvpcMyBCywbS7Mm24Wvhoztm60EiB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}