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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45356b64d61a848020037061f34113ea26d6990e8fe18df8f268e167499ac8aa' 
  AND token = 'W5086nYULeV+77ijm40OBM+3141i/UAg6KF8IeNEm1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}