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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f27169624bab79399c99c1ee6272815af518ae084594e51bfe61241f3a1fc99' 
  AND token = 'IV+sTxUYItTlo9b6VACWEQyTYa73nNPteVJ5b6ya2+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}