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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e81581d59603fadbc259fd4179a4ac52081bf1b1d87c3aea38ad485a7fc5f98' 
  AND token = 'eFp1X4lQmn30jL3PXo22bQM4eKhR0MckAUSD6uCnTVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}