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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ce350e4b43e03323bfe4205996e5b290b110386c2c406fc64ec8914903b5f2' 
  AND token = 'QWpHfbpQr++94/l5um44OuP1U8Cd+xL9NFCxuicFMtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}