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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed8950d8258eece0433059711c1675899f2f7e3e5af0171739732879ee5b048' 
  AND token = 'roGSPpYA52Cps+72fetB7F8Zc4nfwOR/Lx160kpwxus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}