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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '710f06c85b5243508232f570ccc7e181633f0e70c58c6b771b9b8090c3249ac7' 
  AND token = 'S0GMYH4tHnLFrlJ5GxUdTq79OTxDL3rEkCzqcZ8Oc28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}