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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69780a2922b870f6d7d1e839d1d460d52c707cf0f2214b0c4acc22b2bc3dde65' 
  AND token = 'u2KK7SQRiDrdx45sjKqEx0qx2o0Izm+CCoQG0r+tuRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}