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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9884e5c59d6a7f7d52d16e30aed9e9362306e0423545360c4e991139cdb291f0' 
  AND token = 'Wzsfg0QFUb/y5HWFuq8+3tQktDPrstaNUcDvjXlEDmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}