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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b60a2fef0c4af5164669d77da9a56ac8ca0d03a8b47c53237e4583fd7d4d45' 
  AND token = '4YAMsBUkq8l8PD0uo+nN+MdsiUF4maOzVmabY8FKSg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}