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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c7b625218c0d5d7e45ea0c78b29f76edc6131d324df4cd441ee7dfec0ff2dd' 
  AND token = 'i9J7C1Wl8GbE4pnMFQQqWBK/NVBqBLv457OBSj/wMYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}