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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd300524b52ec10080b8aa6d814218c555cef7df674ae8a9ebc574dd8cfbfa41d' 
  AND token = 'd6XNq+EmFM09EFH1ZKGy65nJKxuNVF5wZoz/Aa1hUoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}