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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c536974cee4fe3fc028ef70ed0f1997e96f1c2643f596758f0b59f1ca0a64e0' 
  AND token = 'o/s6zgGGFjrjMvc7upp8vMqPQNs6Ct9pH6dTNN0+/FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}