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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0188ee457ce138719213c06f449da0b8a3973dad753ab0df2a43ef216e4838' 
  AND token = 'jyjNOABV8ybIGgr0i8pV7G86xsAGNRmHeOivc8mEfas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}