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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678eab5821dd44b4e0891da87fa130b2321ecd72a4e510b05102dbe88f504a3d' 
  AND token = '+LVLWQckcOz+XzCtHAwL6PrDWTkoKdxDyl3E7N/uIqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}