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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa2278c24e758ad1b80c001aefc89ef5b4553fffb5ccf529cd0c3db0ac3d2f6' 
  AND token = 'AI1Ktra+xOeGSmMnjMsPcgek/SedQzWWZOWsm/kdsvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}