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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606a927d601ba04dd855c2757be25ed1fa54dc4dcbce39ae4adf5d350afa6b63' 
  AND token = 'XU9Pg0iCvNyAfwU5ioJxjXr6CAXBW3si0kG/ztVpIHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}