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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb191ebfe9ccbd39eefbfcf39110bd05834fe32e40e864481bcff59043ba2b6f' 
  AND token = '7JXB/jN6eq4SDcdRUq+G8sWksDi/NYD/+JUZzY11img=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}