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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80619ccd824414afba6f75094a405b5818a96b497eceb68e342639523ac55a01' 
  AND token = 'orYA0Swcf3y0w9JFn5Nv+GUaXT0T1NLpfQo+wQ8+wJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}