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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aacd3f16982d308f699e010f93935829b66e2b7838ab554615e175b587e382b6' 
  AND token = '4rySrea+VUKVqbnpYUX2n5L0PjPifiaD2HatJyKad7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}