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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62b73ff4cb69c5824da9f6f25ac3df3fa9bbd657f7d3795888e2dee70a698da' 
  AND token = '4KUlYebx2iJRF3Xk8RCUwUYdjJLLcRJ2h/qlQtEFx3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}