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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9081c6ecbae1bdf4d22b5862dfc5bdebc9ce725f44cc1991e561716036bad801' 
  AND token = 'IhYVFhJu/1jqhLLfjpu61WfO4uGDMJ3tK2b7k8KhrbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}