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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b271599a5674c8db561dedde365e93a6dcfd4c1477870b38394e107ac11dd3e6' 
  AND token = '0nrw3PTmPxg+F4qv8puu5Sq5MeJomMygoGZS+b4DYCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}