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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdec48d0441b53187b31205c4afbf6c039342f997fbb11ef24a2a100a3998e4e' 
  AND token = '69v3M26CATKMm6j/3bXssf77lZflbM24gdU3SxdgiCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}