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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cfb5eddc1f31db9394cfb05fe9777fb4779700ba14de5c23514f542ac59c29' 
  AND token = 'bU7IzNgIPfXL7PqSPXiX+gd7fx3Ame1eCuNIYAiLnKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}