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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56ef5f4af6d9bfb34f99d9c52b89a2f8328e772fb1c001c526406dd9da143008' 
  AND token = 'PEryPoRK6RnlVX2n4K9v3QvT3DW+D1Cjx0FX65uNvNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}