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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72be3a1a9007868770d46cba6c702de044bc30a2057d487f249dfeecb817cea3' 
  AND token = '0ON66Snt5LYWM5me0mpUkXqipKSaRBFkGkKglE4kgpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}