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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d4f8c40aad06c4ed426693cc8f0fea4aeaf6d59a45bc719bac2e451b405201' 
  AND token = 'uwu9IXcLHlCAHuDQ9gidz9+CEyplXFtsVV8lVoE3nEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}