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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd3d9c0b28621a8cb727b54ea267442f96e7c1533032bbcf956e1fd644a4730f' 
  AND token = 'I2JVXcfJh+Ch8E2+lLEK8uh8AmjaXA6hDUSmrvjq04U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}