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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5086c916bfa6e30570f8aa366ef4f3645558ef18ebf65e5b5d28e7732e4a73c0' 
  AND token = 'PdWLc0FZmmHO5Mrhi7Hr54mhbIWLoZsmDJ8Z1n4y2nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}