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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ae9fd7624f3eadc8b4ff2fc5dd4c55fec276e21fb1a64ebaced37f061d595f' 
  AND token = '2cqnDSxrA3n9q9j9xCFyDUIbqfk5Xnf9y3txOET5enY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}