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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a357a2e796aa5024c9272ebea7dec5af4a3e40fcf4e49665624d80e8102eec' 
  AND token = 'q9pDBQdYHW7CyEB6+XZ5Qs1Np1kn12feQSpB1bWvQUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}