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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e10331fc7cefde63c80d6452c3c0e2fb58f148f2c209664d326a0a2a8ababfb' 
  AND token = 'hzj2kO/bQq21AiH+l+lNn6KIvmGMdGAP5C0Z/xOHDnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}