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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ef48eac23c3ec8839168dcacc1b86e3f6ce2a3c2ddd307921d94a51a821831' 
  AND token = 'WK0L1V5u1b46uKVZNGx/43PlJsl51mnPbTz3ghiFlMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}